Sunday 17 April 2022

Key to Arthritis Genetic Cure Discovered

 

Key to Arthritis Genetic Cure Discovered

Scientists have known for a long time that autoimmune diseases operate by causing a person’s immune system to mistake its body’s own tissues as foreign, leading it to attack.

Conventional therapy has been to take dangerous immunosuppressive drugs to stop the immune system, but this causes a cascade of terrible side effects.

Now, scientists may have found the specific gene involved in arthritis diseases that attack joints and bone tissue, giving hope that more targeted treatment may be on the horizon.

Researchers at the University of Michigan recently were able to drill down past conventional theories regarding the genetic process that causes rheumatoid and other forms of arthritis.

Scientists have known that a certain gene group, called HLA (human leukocyte antigen) is the culprit in triggering the body’s immune system to mistakenly take joint and bone tissues as foreign. But until now, they never knew specifically which gene in the group was responsible.

Conventional treatment for autoimmune diseases involves suppressing the immune system’s function. However, this treatment is broad- and it causes the body to not be able to ward off many other diseases as a consequence. Diseases like colds, flu, bacterial infections, even cancer end up running unchecked.

But the University of Michigan scientists have discovered how one specific gene, called the shared epitope, actually triggers osteoclasts (which destroy bone) and other destructive proteins to launch their assaults.

Learn more about how to stop inflammation and end arthritis in as little as just 30 days, without dangerous drugs or suppressing the immune system…

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